Journal: Science Progress

Article Title: Characteristics of adults with potential refractory chronic cough identified using an algorithm designed for administrative claims databases: A descriptive study

doi: 10.1177/00368504241238080

Figure Lengend Snippet: Identification of potential RCC cases from Optums Clinformatics Claims database, 2009–2019 (N = 782,121). a Excluding combinations with quinidine. b Excluding codeine combinations with acetaminophen (for pain), butalbital, a barbiturate, aspirin, caffeine, and a methylxanthine (for tension headaches), carisoprodol, and aspirin (for acute, painful musculoskeletal conditions). c A total of 100 adults were excluded due to missing data on sex. d In the year before the index date. e A prescription for roflumilast was used as a proxy for the disease in the absence of a diagnostic code. f A prescription for nintedanib or pirfenidone was used as a proxy for the disease in the absence of a diagnostic code. g A prescription for isoniazid, pyrazinamide, ethambutol, bedaquiline or delamanid was used as a proxy for the disease in the absence of a diagnostic code. ACE: angiotensin-converting enzyme; COPD: chronic obstructive pulmonary disease; RCC: refractory chronic cough.

Article Snippet: We conducted a retrospective cohort study using data from the Optum Clinformatics™ Data Mart, , a large administrative claims database that contains de-identified patient-level information from privately insured and Medicare advantage beneficiaries across all 50 US states.

Techniques: Diagnostic Assay